1. A 39 year old female patient presented with DVT right lower limb. As a part of acute management LMWH was started along with warfarin with a plan to discontinue LMWH heparin in 5 days when INR range of 2-3 will be acheived with warfarin. However on 4th day patient developed purpura with confluent areas of skin necrosis over lower abdomen. Management will include all except?