Drug Review

Antifungals: Ampho B

The first antifungal, amphotericin B deoxycholate, was introduced in 1958. It offers potent, broad-spectrum antifungal activity but is associated with significant renal toxicity and infusion reactions. Lipid-based amphotericin B formulations were introduced in the 1990s and maintain the potent, broad-spectrum activity… Read More ›

Zolendronate & Pamidronate

Bisphosphonates are used as primary therapy for skeletal disorders characterized by excessive or imbalanced skeletal remodeling, leading to excessive osteoclast-mediated bone resorption and that also includes Paget disease of bone, malignancies metastatic to bone, multiple myeloma, and hypercalcemia of malignancy…. Read More ›