21. Methyl Malonic Acid is raised in deficiency of ?
1. Vitamin B12
2. Folate
3. Both Vitamin B12 and Folate
4. None of these
22. Elevated homocysteine is seen in deficiency of ?
1. Both Vitamin B12 and Folate
2. Vitamin B12
3. Folate
4. None of these
23. Most sensitive for detection of Vitamin B12 deficiency is ?
1. Increased MMA
2. Low serum vitamin B12
3. Presence of clinical symptoms
4. Increased Homocysteine
Answer: Correct Answers are option [1] for Q 21, 22, 23
MMA (serum/urine) is increased only in def of B12 whereas Homocysteine is raised in various conditions including deficiency of B12 as well as Folate.
MMA is most sensitive test for detection of B12 deficiency.