68. Target CD34+ ve cells in peripheral blood (PB) graft in Allo HSCT is ?
[1] >/= 4 X 10^6/kg
[2] >/= 6 X 10^6/kg
[3] >/= 8 X 10^6/kg
[4] >/= 10 X 10^6/kg
Answer = [1]
The recommended CD34+ cell dose in a PB graft is at least 4×10^6 CD34+ cells/kg of recipient weight, while a dose of<2×106 CD34+ cells/kg is discouraged to avoid risk of engraftment failure.
Also remember = The recommended cell dose in a BM graft is 4 X 10^8 TNC((total nucleated cells)/kg of recipient weight for hematologic malignancies.