69. Which if the following is best donor for a CMV seronegative recipient ?
[1] CMV Seropositive
[2] CMV Seronegative
[3] Both have same outcome
[4] None of the above
Answer = [2]
CMV remains dormant in leukocytes and can be re‐activated when the host becomes immunocompromised. For a CMV negative patient, ideally, a CMV negative donor should be used, whenever possible to prevent CMV disease in post transplant period.
For patients who are CMV positive, either CMV negative or positive donor can be used. Some centers prefer to use CMV positive donors for CMV positive patients