Reply To: NEET SS Clinical Hematology 2020 Telegram Group Discussion MCQs

18. An iron overload disorder presenting in adulthood with evidence of microcytic anemia, diabetes, peripheral retinal degeneration, dystonia, dementia, or dysarthria is s/o 1. Haemochromatosis type 3 2. Aceruloplasminemia 3. Juvenile haemochromatosis 4. Classical haemochromatosis Answer = Aceruloplasminemia Neurological expression is a key feature of the disease. Hereditary Aceruloplasminemia is the sole form of adult genetic iron overload in which excessive iron deposition occurs in the brain. Movement disorders can be present as well as psychiatric symptoms. Retinal degeneration is one of the consequences of the disease.