Transfusion Medicine Review -2 (10Q)

This section contains 10 True/False Questions from Basics of transfusion medicine which should be known to Hematologists.

This Q are to be answered as true and False.

Marking > 1 mark for Correct response and 0 for wrong response. 

1. Intravascular hemolysis, renal dysfunction, and progression to DIC are rare with delayed hemolytic transfusion reactions (DHTR).

2. Patient with frequent febrile reactions should receive leukoreduced products.

3. IgA deficiency must be excluded when anaphylactic reactions develop to blood products.

4. Typical features of TRALI include acute respiratory distress, tachycardia, raised blood pressure and evidence of positive fluid balance.

5. TRALI results from the transfusion of plasma containing blood components.

6. In an emergency when blood groups are not available O Rh(D) negative unit is most suitable for transfusion of FFP.

7. Child with sickle cell disease on a regular transfusion program is most likely to have positive antibody screen.

8. Neonatal Alloimmune Thrombocytopenia (NAIT), especially with a low platelet count (< 30 – 50,000 plts/µl), will require a platelet transfusion and fathers aphresis platelet is best source of PLT in such neonates.


9. Intracellular 2,3 DPG falls and approaches zero by 14 days of storage but then returns to normal levels in 24 hours after transfusion to the recipient.

10. A patient with TTP undergoing therapeutic apheresis (Plasmaphresis) requires cryoprecipitate priming before plasma is administered.


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