Transfusion Medicine Review -1 (15Q)

This section contains 15 True/False Questions from Basics of transfusion medicine which should be known to Hematologists.

This Q are to be answered as true and False.

Marking > 1 mark for Correct response and 0 for wrong response. 

1. Platelets and granulocytes are not functional in whole blood units.

2. RBCs are administered over a maxium period of 4 hours thruough a 100-micro m filter.

3. In most stable asymptomatic patients without cardovascular disease, transfusion is initiated if hemoglobin is <10 g/dL.

4. Shelf life of PRBC units is 35 days in CPDA- 1

5. Washed PRBC units are used in patients with severe IgA deficiency.

6. Shelf life of Washed PRBC unit is 4 days. 

7. Leucocyte reduced PRBC units are defined by those containing <10 X 106 WBCs per unit. 

8. Single-donor aphersis Platelets are collected from single donors by apheresis and it contains >/= 3 X 1011 platelets in 250-300 mL plasma.

9. Shelf life of SDP (Single donor platelets) is 5 days. 

10. When replacing coagulation factors, a dose of 50 mL/kg of FFP is recommended, with periodic monitoring of coagulation tests to determine eficacy and appropriate dosing intervals.

11. Each unit (bag) of cryoprecipitate increases fibrinogen level by 5-10 mg/dL in a normal adult. 

12. RBCs, platelets, and graulocytes are irradiated with 25 G of gamma radiation to prepare irradiated products.

13. All cellular components that are Leukoreduced are considered “CMV-safe”.

14. Leukoreduction of blood products prevents TA-GVHD (Transfusion associated graft versus host disease).

15. FFP and cryoprecipitate do not transmit CMV infection. 


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