ISTH DIC Scoring

The ISTH scoring system for DIC evaluates: (a) platelet count, (b) prothrombin time (PT), (c) fibrin-specific marker(s) (e.g., fibrin monomer, fibrin D-dimer, fibrin split products), (d) fibrinogen.

Platelet Count
> 100,000/microL (0 points)
50,000/microL – 100,000/microL (1 point)
< 50,000/microL (2 points)
Increase in Fibrin Markers
No change (0 points)
Moderate rise (2 points)
Strong rise (3 points)
Prothrombin Time Prolongation
3 seconds or less (0 points)
> 3 seconds but < 6 seconds (1 point)
Greater than 6 seconds (2 points)
Fibrinogen Level
Greater than 1 g/L (0 points)
Less than 1 g/L (1 point)

Sum of all 4 points : DIC Score Interpretation

0-4 points: DIC is not overt, repeat score in 1-2 days
5-8 points: DIC probable, repeat score daily
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