Hepatic and Renal dose adjustments of Chemotherapy Drugs

Hepatic & Renal dose adjustments of Chemotherapy Drugs The Drugs which are in bold, details of dose reductions are mentioned below table, scroll down.¬† GuideLines for Chemotherapy Dosage Adjustment Adjust if Function Impaired Hepatic Renal Alemtuzumab No No Arsenic trioxide Read More …

Zolendronate & Pamidronate

Bisphosphonates are used as primary therapy for skeletal disorders characterized by excessive or imbalanced skeletal remodeling, leading to excessive osteoclast-mediated bone resorption and that also includes Paget disease of bone, malignancies metastatic to bone, multiple myeloma, and hypercalcemia of malignancy. Read More …

Tumor Lysis Syndrome

Metabolic derangements that occur with tumor Breakdown Spontaneous (Less common associated usually with normal Phosphorus levels) > may occur with high tumor burden (i.e. hyperleukocytosis) Post Cytotoxic therapy Tumor cytotoxicity releases intracellular contents,vincluding nucleic acids, proteins, and electrolytes into the Read More …