Category: Supportive Care Notes
Hepatic and Renal dose adjustments of Chemotherapy Drugs
Hepatic & Renal dose adjustments of Chemotherapy Drugs The Drugs which are in bold, details of dose reductions are mentioned below table, scroll down. GuideLines for Chemotherapy Dosage Adjustment Adjust if Function Impaired Hepatic Renal Alemtuzumab No No Arsenic trioxide Read More …
Zolendronate & Pamidronate
Bisphosphonates are used as primary therapy for skeletal disorders characterized by excessive or imbalanced skeletal remodeling, leading to excessive osteoclast-mediated bone resorption and that also includes Paget disease of bone, malignancies metastatic to bone, multiple myeloma, and hypercalcemia of malignancy. Read More …
Tumor Lysis Syndrome
Metabolic derangements that occur with tumor Breakdown Spontaneous (Less common associated usually with normal Phosphorus levels) > may occur with high tumor burden (i.e. hyperleukocytosis) Post Cytotoxic therapy Tumor cytotoxicity releases intracellular contents,vincluding nucleic acids, proteins, and electrolytes into the Read More …